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Entities enabling scientific fraud at scale are large, resilient, growing (2025)

https://doi.org/10.1073/pnas.2420092122
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It kinda skips over how large mainstream journals, with their restrictive and often arbitrary standards, have contributed to this. Most will refuse to publish replications, negative studies, or anything they deem unimportant, even if the study was conducted correctly.
So much of this started with the rise of the peer-review journal cartel, beginning with Pergamon Press in 1951 (coincidentally founded by Ghislaine Maxwell's father). "Peer review" didn't exist before then, science papers and discussion was published openly, and scientists focused on quality not quantity.
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Maybe we need a journal completely dedicated to replication studies? It would attract a lot of attention I think.
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And funding dedicated to replication studies.
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This is Goodhart's law at scale. Number of released papers/number of citations is a target. Correctness of those papers/citations is much more difficult so is not being used as a measure.

With that said, due to the apparent sizes of the fraud networks I'm not sure this will be easy to address. Having some kind of kill flag for individuals found to have committed fraud will be needed, but with nation state backing and the size of the groups this may quickly turn into a tit for tat where fraud accusations may not end up being an accurate signal.

May you live in interesting times.

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It is useful to distinguish between "effective" scientific fraud, where some set of fraudulent papers are published that drive a discipline in an unproductive direction, and "administrative" scientific fraud, where individuals use pseudo-scientific measures (H-index, rankings, etc) to make allocation decisions (grants, tenure, etc). This article suggests that administrative scientific fraud has become more accessible, but it is very unclear whether this is having a major impact on science as it is practiced.

Non-scientists often seem to think that if a paper is published, it is likely to be true. Most practicing scientists are much more skeptical. When I read a that paper sounds interesting in a high impact journal, I am constantly trying to figure out whether I should believe it. If it goes against a vast amount of science (e.g. bacteria that use arsenic rather than phosphorus in their DNA), I don't believe it (and can think of lots of ways to show that it is wrong). In lower impact journals, papers make claims that are not very surprising, so if they are fraudulent in some way, I don't care.

Science has to be reproducible, but more importantly, it must be possible to build on a set of results to extend them. Some results are hard to reproduce because the methods are technically challenging. But if results cannot be extended, they have little effect. Science really is self-correcting, and correction happens faster for results that matter. Not all fraud has the same impact. Most fraud is unfortunate, and should be reduced, but has a short lived impact.

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My wife completed her PhD two years ago and she put a LOT of work into it. Many sleepless nights, and it almost destroyed our marriage. It took her about 6 years of non-stop madness and she didn’t even work during that time. She said that many of her colleagues engaged in fraudulent data generation and sometimes just complete forgery of anything and everything. It was obvious some people were barely capable of putting together coherent sentences in posts, but somehow they generated a perfect dissertation in the end. It was common knowledge that candidates often hired writers and even experts like statisticians to do most of the heavy lifting. I don’t know if this is the norm now, but I simultaneously have more respect and less respect for those doctoral degrees, knowing that some poured their heart and soul into it, while others essentially cheated their way through. OTOH, I also understand that there may be a lot of grey area.

My eyes have been opened!

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the problem is two-fold in my opinion.

firstly, there are basically no legal repercussions for scientific misconduct (e.g. falsifying data, fake images, etc.). most individuals who are caught doing this get either 1) a slap on the wrist if they are too big to fail or in the employ of those who are too big to fail or 2) disbarred, banned, and lose their jobs. i don't see why you can go to jail for lying to investors about the number of users in your app but don't go to jail for lying to the public, government, and members of the scientific community about your results.

secondly, due to the over production of PhD's and limited number of professorship slots competition has become so incredibly intense that in order to even be considered for these jobs you must have Nature, Cell, and Science papers (or the field equivalent). for those desperate for the job their academic career is over either way if they caught falsifying data or if they don't get the professorship. so if your project is not going the way you want it to then...

sad state of things all around. i've personally witnessed enough misconduct that i have made the decision to leave the field entirely and go do something else.

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One approach is more integration of researchers with businesses. Fraud (or simple incompetence) by researchers negatively affects businesses, as they expend effort on things that aren't real. I understand this is a constant problem in the pharmaceutical industry.
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The future of science, the Internet, and all things: The Library of Babel by Jorge Luis Borges.

Some things should not have been democratized. Silicon Valley assumes that removing restrictions on information brings freedom, but reality shows that was naïve.

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