The annoying thing is that we could’ve been simulating long duration partial gravity using artificial gravity for decades, but NASA has refused to do so. For inexplicable reasons. If I had to guess, it’s due to the microgravity research community fiefdoms who have made a career of microgravity health effects and so don’t like the idea of directly addressing them using artificial gravity as it makes a whole career’s worth of work largely obsolete.
Not if you want it dependable enough to entrust a multi billion dollar project and several people’s lives to it.
People talk about the moon mission like some massive conquest of space, but we needed to get the fuck off the moon much past sunrise or astronauts would have cooked. It was based on extremely limited oxygen supplies and involved significant radiation exposure that was only ok because again we ran away from an extremely inhospitable environment before things went wrong.
Even today the ISS benefits from earths magnetic field, its space light not a true replica of a mars mission.
The biggest problem is that people have really lost the ability to think big. There's always infinite reasons to not do something, and there will never be a perfect time. So at some point you simply have to choose to push forward. Like Kennedy put it:
"We choose to go to the moon. We choose to go to the moon in this decade and do the other things, not because they are easy, but because they are hard, because that goal will serve to organize and measure the best of our energies and skills, because that challenge is one that we are willing to accept, one we are unwilling to postpone, and one which we intend to win, and the others, too."
The mention of "quality factor" here just begs the question. The reason we need research on biological effects of high-Z ion exposure is that it has a different mechanism of damage, not captured by that paradigm.
A hypothetical 500 day mars mission is ~1 Sv optimistically which is something like 5% fatal cancer risk. A 3 year mission you’re well above that even before considering solar storms etc.
I think many would sign up for a mars mission especially as treatment improves, but there’s only so much wiggle room here.