We are in fact far more ready for sending crewed missions to Mars than we were to sending crewed missions to the Moon when JFK made his Moon speech. We had only barely launched an astronaut on a suborbital flight at that time! And yet 7 years later…
I'm confident that if they tried to launch a Mars mission with current-day technology now, the crew wouldn't make it. Nobody's ever been in space for that long, to start - yet Musk wants to deorbit the ISS, the only viable platform at the moment to even try and simulate a two year space trip.
The annoying thing is that we could’ve been simulating long duration partial gravity using artificial gravity for decades, but NASA has refused to do so. For inexplicable reasons. If I had to guess, it’s due to the microgravity research community fiefdoms who have made a career of microgravity health effects and so don’t like the idea of directly addressing them using artificial gravity as it makes a whole career’s worth of work largely obsolete.
The track record for successfully landing on Mars isn't that awesome:
> Historically, counting all missions by all countries, there has been about a 50% success rate at Mars — and the odds of successfully landing on Mars are only about 1 in 3.
When JFK made the speech, it was in the middle if the cold war and there was a realistic fear that the "capitalist way if life" could be beaten by command economics of the Soviet Union in cutting edge science and rocketry, justifying the huge amounts invested in the space race. What is the impetus now? We're all about government efficiency in cutting the social-safety nets, scientific research, but we'll carve out a Mars mission "because it's hard"?