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Buildings and bridges have very large safety margins, to account for design errors, construction errors, damage, poor materials, etc.

Airplanes have much smaller safety margins, meaning a lot more calculation is done, and there's a high emphasis on double checking everything.

Spacecraft have tiny safety margins, which amps up the design rigor to 11.

Airplanes and srarcrafts are operated by a trained trusted crew. Software is operated continuously by lots of hostile people and machines.

When terrorists take the control of a plane, it's a catastrophe.