> Booster Systems Engineer Jenny M. Howard acted quickly to recommend that the crew inhibit any further automatic RS-25 shutdowns based on readings from the remaining sensors,[6] preventing the potential shutdown of a second engine and a possible abort mode that may have resulted in the loss of crew and vehicle (LOCV)

Incredible that human action during ascent (when everything is usually automated) potentially saved a crew. One of probably dozens of cases, is my guess.

STS still has the record for most astronauts killed. I don't believe we will surpass that grim record until Starship starts carrying humans.