(The key thing to remember is that sugar is bad for you; it's not that HFCS is good, but rather that cane sugar is just as harmful.)
Two fun additional notes:
* There's a video somewhere showing how cane sugar breaks down into fructose and glucose in bottled sodas anyways, and
* Perhaps unsurprisingly, taste testers can't reliably distinguish between HFCS and cane sugar formula Coke.
Yes, sugar breaks down to the same fructose and glucose proportion.
That takes months. Even longer in concentrated syrup form. Even longer in the one of two components that bottlers get to make the syrup.
A freshly bottled coke in a glass bottle still has the undivided sucrose and that is why it tastes more crisp. After a while, it separates and it doesn’t taste any better because it physically isn’t different.
A freshly bottled HFCS coke still tastes fresh in all other respects, but is essentially stale on day one as far as the sweetener goes.
But by far the best is a properly calibrated soda machine with fresh syrup— but it’s only really fresh if it is sucrose. Otherwise it’s basically stale before you even make it.
The half-life of sucrose in coke under good storage conditions is ~2 weeks[0]. Modestly higher temperatures, such as during transport, reduces that to hours. The internet suggests that that coke is typically consumed 4-12 weeks after manufacturing, depending on the supply chain. Even in the most optimistic scenario, no more than 25% of the sucrose remains when you drink it. Realistically, it will round to 0%. Almost no one has drank a coke that still had sucrose in it.
The process is slower than enzymatic catalysis in the body (seconds to minutes) but still quite fast.
[0] I used an LLM to run the math but the result passes a cursory eyeball test.
The half-life of sucrose is greatly reduced by acidity and to a lesser extent temperature. It is stable for centuries in a neutral pH when kept cool but that describes almost nothing we do with sugar in foods.
You can get the US formula coke with cane sugar during Passover in markets with a high Jewish population. Taste it, it'll be practically the same as HFCS US Coke and not like Mexican Coke. Because, it has the same amount of salt as the US variety.