Yes and no, depend on your expectations. Some/many like to run local LLMs just for the sake of it, so anything will do.
MoE are useful on PC systems, at the condition of having high enough memory bandwidth (and large amounts of RAM) - that is, Threadripper/Pro.
The advantage of MoE is that only a subset of the model's experts is used for each token, so not all weights need to be present in VRAM at once. The remaining weights can reside in system RAM, although moving and accessing them still carries a substantial performance cost (and that's why high memory bandwidth is needed).
I've been building a SaaS that deals with data that can't be distributed to third parties. Some of the useful AI stuff I can add is not time sensitive and can run overnight. Things like this allow me to use higher quality models without selling my house for GPUs.
If so, I could use a larger model than I have real-time hardware for. The largest, well-trained models can often get the output mostly right in one try. I also would be using AI's as a supplement to, not replacement for, my own brain. So, issues with the outputs wouldn't be a problem because I'm just keeping what's helpful.
If I still need to re-generate it all, it might still save money over time by avoiding cloud costs. Also, hardware that's already paid for is a sunk cost that doesn't inflate over time. Glitches in loading or destroying VM's might blow up into a big bill.