I have recently completed building a large native macOS app and my take is that, for 90% of work, SwiftUI is good but for the 10% you would need AppKit.

For my app which is a AI chat app, I needed to load and show a large number of chat items in a list, SwiftUI is really bad at this. Another issue is, most of Swift markdown libraries don't perform perform well because each elements are rendered as SwiftUI views which introduced a lot of issues So I built my own renderer using TextKit. Even basic things like Settings window is broken. But I still prefer using SwiftUI as It gets the work done faster and I can always fallback to AppKit.

I find that web tech like React are worst than SwiftUI. React also has re-rendering and state management issues