Thanks. With the relative speeds, I'd guess the Falcons would use an attack profile similar to ground strafing - letting them pass well above the cloud of debris. Any thoughts?
Also, Wikipedia gives a 3km effective firing range for the M61 - but it'd be no surprise if the F-16's standard targeting optics can't achieve that against small airborne targets.
This video shows a Ukrainian F-16 doing just that along with reactions from a pair of experienced US fighter pilots. It seems they're shooting from closer than 3km.
Far closer, because (my impression) the F-16 has nothing resembling the targeting systems you'd want for this job.
Hopefully a decent defense contractor or few sees business opportunities here.