Video games are an interesting analogy since they often trade security for performance, trusting clients about world state quite a bit.

Finance and biology do come across as two similar high level systems. But while we can employ KYC, fraud detection, and various auditing techniques to finance, I don’t know what you do for biology. You can easily run an algorithm over every transaction a person makes in their account but there’s no equivalent for every cell, every bacteria strain, every virus in the human body.

I'm bullish on mRNA vaccine technology to release the "patches" much more quickly. there was widespread resistance to this during covid, but covid wasn't horribly lethal. if airborne Ebola spread as productively as covid, for example, I doubt there'd be many anti-vaxxers left (one way or another!) the acceleration of biology research that might accelerate pathogen development should also accelerate the development of broad-spectrum mRNA vaccines with high persistence.

also, afaik the most effective way of developing pathogens is through serial passage through humanized mice or something like that - directed evolution at a small scale, selecting for traits. AI simply isn't needed for that. I don't think information or intelligence has been the bottleneck for bioterrorism, it's motivation and resources - same as for any other kind of biology research program.