Not to subtract from anything you said, but something that could help us, in the aggregate, as a society, is to frame things differently.

Today, most people say "human biology is a thing of wonder" "Humans are built for longevity". And when a terrible ailment strikes, they explain it with "The meaning of life/God/The devil/We must die of something!"

In my mind, we could create a human systems biology profession where students are told during the first day at school "human biology is a mess wrought up by mindless evolution. Your job is to bring it to the exacting standards of perfection that we are able to apply to other things. In the measure we succeed, we will be able to bring dignity to billions of people."

To add something, glioblastoma multiforme is really weird and our understanding of it is severely limited.

Lead paint/gasoline. Asbestos. Teflon. Chernobyl. Weedkiller. Just what I can think of since the 70s.

Yes. Modern life is a chemistry experiment. We are also exposed to various forms of radiation on a regular basis.