Yes. They don't actually care about the drug part anyway, beyond the excuse it gives them to operate outside their jurisdiction. We already have sane laws to cover the other crimes a "cartel" might do.

To be fair for the literal example prohibition is what creates the drug cartels in the first place so it is more coherent than it sounds at first blush. Enforcement is effectively a subsidy to those who don’t get caught.

For social media it is a whole different problem from it being entangled with protected speech. We don't want 'arrested for spreading misinformation defined as anything which contradicts the offical line' to be a thing.