I disagree a bit with the neuroticism and agreeableness being so obvious. There are many professions I would be TERRIBLE at precisely because I am so agreeable. And, I have real world experience with a business partner that is MUCH higher in neuroticism than I, and much less agreeable. Both sides of that spectrum have their strengths. We often have opposite approaches sometimes, but both can work, and one isn’t obviously better in all circumstances.

And introversion can be a wonderful asset in some professions as well.

However, I do agree that conscientiousness is probably pretty universally better.