No issues per se, but academic publishing has deep roots in the latex ecosystem. So templates from publishers are often not available in typst, or the publisher insists on a latex formatted file.

Often supervisors/professors etc will also resist using typst because of the cognitive overhead on their already oversubscribed time. Typst has about 40 years of history to overcome and that will take a long time to do.

They made a new format with basically no accessibility. We finally got latex usable by blind people with acceptable html output, I’m not moving to something worse.