Not only are there tons of papers, there are off-label treatments (some that have improved more than 80% of the folks I'm about to mention), and this isn't just about age related decline, but cognitive impairment in general. Long COVID, ME/CFS, TBIs, and other conditions are widely considered to have a similar origin. If you are interested in this stuff, I encourage you to look up all the scientific papers on this. It is fascinating stuff.