I help run our bug bounty program at a mid-sized company, and we regularly get subdomain-takeover submissions where the reporter has put zero effort into validating the report before submitting it.
They appear to be running some subdomain or certificate search for our domains, then running curl over the results. If they get a 404 they submit it to us as a subdomain-takeover report.
We use a bunch of vendors where we've got foo.example.com CNAMED over to the vendor, but the vendor's servers only serve traffic off some sub-path, and requests to https://foo.example.com/ are going to get 404.
So, I could understand larger organisations simply banning them outright.