Yeah, that’s the part the legal system has a hard time with. We don’t have definitions or suitable penalties for these things
I mean, I’m not sure Pablo Escobar ever sold drugs or murdered anybody with his own hands. Metaphorically though there was a ton of blood on his hands. Charles Manson allegedly never killed anybody himself either. But we generally agree these guys were bad for society.
I’m generally lasseiz-faire about drugs, and I generally put the onus of responsibility on the person choosing to ingest them.
But there are some drugs, like opioids, that kind of transcend that. They cannot reasonably be safely used in a recreational manner, and are objectively a cancer to society.