How exactly?
Harris didn't run even a center-left campaign, she pushed center-right except on a few issues at the margins and it was late in the game on that front.
Americans generally favor more liberal policies economically, like stronger labor rights, universal healthcare, student debt cancellation etc. There was a lot to offer voters of all stripes there.
I think too many Democrats counted on a huge pro abortion turn out of women specifically and that translating into democratic votes, which, even to my surprise, it did not.
Take a look at the results of the various referendums. Some of the same states that have voted for Trump with a hefty margin also voted for things like raising minimum wage or guaranteed paid sick leave.
I think most conservatives have a strong idea in their mind of who their idealogical opponents are: ivory-tower academics, liberal business people and politicians, and all the plebs who side with them to push ideologies and social policies they don't want (policies like people born as men competing with women in sports).
Harris did nothing to distance herself from being strongly associated with that liberal cohort. Regarding social policy and ideology, she came off as being far-left to the average conservative.
Have you ever considered that the stance regarding pro aboriton amongst women is to a certain extend age dependant? What I have noticed anecdotally amongst my acquintances is that older women tend to change their mind on that matter, at least sometimes. I am suspecting this has has plain egotistical reasons, simply because they no longer have to care, paired with a certain amount of women that had an abortion and never really managed to find peace with themselves about it. TL;DR: Careful, not all women are pro abortion, possibly not even the majority.