There is a startup attempting to use ML to find cheaters: https://www.youtube.com/watch?v=LkmIItTrQP4 (this video might be overly optimistic) - https://anybrain.gg

They even claim to be able to fingerprint players according their playstyle, thwarting all methods of ban evasion. Skepticism should be abundant here, but this one of the oldest tricks in ML: categorization/clustering. I'm cautiously hopeful.

This would be server-side by nature.