For server side, you'll likely need a different build of Wasm SQLite, that handles concurrency (and file locking) differently.

Also, WASI is very far from answer (so far). The SQLite amalgamation builds fine for WASI but concurrency is an unsolved issue.

I had to build a VFS from scratch to get my Wasm based SQLite driver into a usable shape.

https://github.com/ncruces/go-sqlite3/blob/main/vfs/README.m...